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Impurity of Cilastatin API
Cilastatin Ph. Eur. impurity I
Impurity
GS.64.CIL.09_1775724856.png
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Product Name Cilastatin Ph. Eur. impurity I
Product Category Impurities, Intermediates
Sub-Category Pharmaceutical Standards, Fine Chemicals, Phosphorylating and Phosphitylating Agents, Amines
CAS No 1174657-12-5
Catalog Number GS.64.CIL.09
Chemical Name/Synonyms (E)-7-(((R)-2-Amino-2-carboxyethyl)thio)-2-((S)-2,2-dimethylcyclopropane-1-carboxamido)hept-2-enoic acid sodium salt ; (2E)-7-[[(2R)-2-Amino-2-carboxyethyl]sulfanyl]-2-[[(1S)-2,2-dimethylcyclopropane-1-carbonyl]amino]hept-2-enoic acid Sodium Salt ; (2E)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid Sodium Salt.
Molecular Weight 358.45 : 23.0
Molecular Formula C16H26N2O5S : Na
Purity NLT 95%
Appearance Light Orange Solid
Solubility Methanol, Water
Applications Cilastatin Ph. Eur. impurity I may be an enzyme found in the kidney and is responsible for degrading the antibiotic imipenem. It is inhibits the human enzyme dehydropeptidase.
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