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Impurity of Bupropion Hydrochloride
Bupropion Inhouse Impurity 10 / 3-Chloropropiophenone
Impurity
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Product Name Bupropion Inhouse Impurity 10 / 3-Chloropropiophenone
Product Category Impurities, Intermediates
Sub-Category Pharmaceutical Standards, Fine Chemicals, Aromatics
CAS No 936-59-4
Catalog Number GS.48.BUP.40
Chemical Name/Synonyms 1-Phenyl-3-chloro-1-propanone; 3-chloro-1-phenylpropan-1-one;2-Chloroethyl Phenyl Ketone; 3-Chloro-1-phenyl-1-propanone; NSC 227202; NSC 37238; β-Chloroethyl phenyl ketone; β-Chloropropiophenone; ω-Chloropropiophenone;
Molecular Weight 168.62
Molecular Formula C9H9ClO
Purity NLT 95 %
Appearance Off-White to Pale Yellow Solid
Solubility Chloroform, Methanol
Applications It was also used in the synthesis of (R)-3-chloro-1-phenyl-1-propanol via asymmetric reduction using in-situ generated oxazaborolidine catalyst derived from (S)-α,α-diphenylprolinol. It is a precursor of phenyl vinyl ketone.
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