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Impurity of Afatinib API
Afatinib Inhouse Impurity 6 / N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
Impurity
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Product Name Afatinib Inhouse Impurity 6 / N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
Product Category Impurities, Intermediates
Sub-Category Heterocycles, Pharmaceutical Standards, Aromatics, Amines
CAS No 179552-74-0
Catalog Number GS.25.AFT.36
Chemical Name/Synonyms N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-quinazolinamine
Molecular Weight 348.72
Molecular Formula C15H10ClFN4O3
Purity NLT 98%
Appearance yellow to light brown crystalline powder
Solubility DMSO, Methanol
Applications N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib; an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs
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